RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-21a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining etc.
Target
CADM1
Pathway
JAK-STAT SIGNALING PATHWAY
PubMed ID
Title
MiR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway
Year
2017
Function
"miR-21 overexpression promotes cardiac fibrosis via STAT3 signaling pathway by decrease CADM1 expression, indicating miR-21 as an important signaling molecule for cardiac fibrotic remodeling and atrial fibrillation(AF)."